GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs11190604 | 1 | rs35106985 | chr10:102307542 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs979233 | 1 | rs35477332 | chr5:42420637 | C5orf51 | chr5:41904470-41921737:+ | -0.45 | -5.41 | 1.41E-6 | Systemic lupus erythematosus |
| UVM | cis | rs10935120 | 1 | rs35718987 | chr3:134272783 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.87 | 6.1E-9 | Height |
| UVM | cis | rs1411478 | 1 | rs3747957 | chr1:180953853 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.69 | 5.07E-7 | Progressive supranuclear palsy |
| UVM | cis | rs11190604 | 1 | rs3750626 | chr10:102266316 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750627 | chr10:102275642 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750629 | chr10:102275727 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750630 | chr10:102275780 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750633 | chr10:102308214 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750719 | chr10:102248950 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3750720 | chr10:102248884 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs3763695 | chr10:102269206 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs9876781 | 1 | rs3774808 | chr3:48481647 | TREX1 | chr3:48501186-48509043:+ | -0.4 | -5.1 | 4.38E-6 | Longevity |
| UVM | cis | rs703842 | 1 | rs3782130 | chr12:58161898 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs1411478 | 1 | rs3789362 | chr1:180951692 | STX6 | chr1:180913175-180992046:- | -0.58 | -5.69 | 5.07E-7 | Progressive supranuclear palsy |